赵伟栋，博士，教授，邮箱：zhaowd@gmu.edu.cn

长期从事生物物理和纳米医学等方面的研究工作，具体为利用原子力显微镜和超分辨荧光显微镜等单分子技术手段来对蛋白等生物大分子和细胞等进行生理条件下单分子水平上的结构和功能的研究。国际上首次确认了红细胞膜中脂筏的存在；提出了一种新的体细胞膜的模型；在单分子水平上定位了细胞膜上表皮生长因子受体和多种糖类等生物分子，发现了这些分子的数量和作用力在癌症的侵袭和转移过程中所发挥的作用。全面系统研究了神经系统中细胞和组织的电学性质，为单分子水平上研究细胞的电学性质以及阿尔兹海默综合征的早期诊断开辟了新的途径和方法。在Small和Acta Biomaterialia等SCI期刊发表论文18篇（其中包括2篇封面文章）。

入选人才项目和称号：

1.江西省“双千计划”创新领军人才长期项目-青年类，100万元

2.赣州市“苏区之光”人才计划科技创新人才培养专项-自然科学类，15万元

主持的基金：

1．国家自然科学基金青年科学基金, 24万元,主持,在研

2.江西省中央引导地方科技发展资金项目, 25万元,主持,结题

3.赣南医学院博士启动经费, 60万元,主持,在研

4.赣南医学院校级课题, 2.5万元,主持,在研

已经发表的论文（其中#为共同第一作者，*为通讯作者）：

1. Mingjun Cai^#;Weidong Zhao^#; Xin Shang; Junguang Jiang; Hongbin Ji; Zhiyong Tang^*; Hongda Wang^*; Direct Evidence of Lipid Rafts by in situ Atomic Force Microscopy,Small, 2012, 8(8): 1243-1250 (封面文章)

2.Weidong Zhao; Mingjun Cai; Haijiao Xu; Junguang Jiang; Hongda Wang^*; A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells,Nanoscale, 2013, 5(8): 3226-3229

3.Weidong Zhao; Shuheng Liu; Mingjun Cai; Haijiao Xu; Junguang Jiang; Hongda Wang^*; Detection of carbohydrates on the surface of cancer and normal cells with topography and recognition imaging,Chemical Communications, 2013, 49(29), 2980-2982 (封面文章)

4.Weidong Zhao^#; Yongmei Tian^#; Mingjun Cai^#; Feng Wang; Jiazhen Wu; Jing Gao; Shuheng Liu; Junguang Jiang; Shibo Jiang^*; Hongda Wang^*; Studying the Nucleated Mammalian Cell Membrane by Single Molecule Approaches,Plos One, 2014, 9(5),e91595

5.Weidong Zhao^#; Yangang Pan^#; Jiazhen Wu; Mingjun Cai; Yongmei Tian; Haijiao Xu; Lihua Yu; Hongda Wang^*; Mapping the resting and stimulated EGFR in cell membranes with topography and recognition imaging,Analytical Methods, 2014, 6(19): 7689-7694

6.Weidong Zhao; Wei Cui; Shujun Xu; Yuanyuan Wang; Ke Zhang; Deyu Wang; Ling-Zhi Cheong; Flemming Besenbacher^*; Cai Shen^*; Direct investigation of charge transfer in neurons by electrostatic force microscopy,Ultramicroscopy, 2019, 196, 24-32

7.Weidong Zhao; Wei Cui; Shujun Xu; Deyu Wang; Ling-Zhi Cheong; Cai Shen^*; Direct Study of Electric Properties of PC12 Cells and Hippocampal Neurons by EFM and KPFM,Nanoscale Advances, 2019, 1, 537-545

8.Weidong Zhao; Ling-Zhi Cheong; Wei Cui; Shujun Xu; Cai Shen^*; A Case Study of the Electrical Properties of Astrocytes by Multimode AFM,Journal of Microscopy, 2019, 275(2), 75-81

9.Weidong Zhao; Ling-Zhi Cheong; Shujun Xu; Wei Cui; Shuang Song; Christopher J. Rourk; Cai Shen^*; Direct investigation of current transport in cells by conductive atomic force microscopy,Journal of Microscopy, 2020, 277(1): 49-57

10.Weidong Zhao; Wei Cui; Shujun Xu; Ling-Zhi Cheong; Cai Shen^*; Examination of Alzheimer’s disease by a combination of electrostatic force and mechanical measurement,Journal of Microscopy, 2019, 275(1), 66-72

11. Ling-Zhi Cheong^#;Weidong Zhao^#; Shuang Song; Cai Shen^*; Lab on a tip: Applications of functional atomic force microscopy for the study of electrical properties in biology,Acta Biomaterialia, 2019, 99, 33–52

12.Zhao Weidong; Song Wentao; Cheong Ling-Zhi; Wang Deyu; Li Hong; Flemming Besenbacher; Huang Fuqiang; Shen Cai^*; Beyond imaging: Applications of atomic force microscopy for the study of Lithium-ion batteries,Ultramicroscopy, 2019, 204: 34-48

13. Yongmei Tian; Jiahan Li; Mingjun Cai;Weidong Zhao; Haijiao Xu; Yi Liu^*; Hongda Wang^*; High resolution imaging of mitochondrial membranes by in situ atomic force microscopy.RSC Advances, 2013, 3 (3), 708-712;

14. Li Ren, Zheng Ma; Qinglan Li;Weidong Zhao; Ye Wang; Hongda Wang; Liqiao Shen; Chengkai Zhang; Xuexun Fang^*; Jihong Yu^*; Identifying a Membrane type 2 matrix metalloproteinase-targeting Peptide for Human Lung Cancer Detection and Targeting Chemotherapy with Functionalized Mesoporous Silica.ACS Applied Bio Materials, 2019, 2 (1), 397.

15. Xueqi Sun^#, Qirui Huang^#, Fang Peng, Jian Wang,Weidong Zhao; Guangxiu Guo^*, Expression and Clinical Significance of HKII and HIF-1α in Grade Groups of Prostate Cancer,Frontiers in Genetics, 2021, 12(1053).

16. Xinwei Zhu, Yingxi Chen, Renjian Xie, Haijian Zhong,Weidong Zhao, Yang Liu^*and Hui Yang^*, Rapid gelling of guar gum hydrogel stabilized by copper hydroxide nanoclusters for efficient removal of heavy metal and supercapacitors,Frontiers in Chemistry, 2021, 9(1019).

17. Bin Fang; Li Zhao; Xiaowei Du; Qiyuan Liu; Hui Yang; Fangzuo Li; Yaohuan Sheng;Weidong Zhao^*; Haijian Zhong^*; Studying the Rhodopsin-Like G Protein Coupled Receptors by Atomic Force Microscopy,Cytoskeleton, 2021, 78(8):400-416.

18. Li Zhao^#; Xiaowei Du^#; Bin Fang; Qiyuan Liu; Hui Yang; Fangzuo Li; Yaohuan Sheng; Xiangfu Zeng; Haijian Zhong^*;Weidong Zhao^*, Direct Investigations of the Electrical Conductivity of Normal and Cancer Breast Cells by Conductive Atomic Force Microscopy,Ultramicroscopy, 2022

发明专利

一种原子力显微镜探针及其制备方法和应用, 2020