赵娜，女，汉族，黑龙江齐齐哈尔人，博士，硕士研究生导师。2010.10-2014.3于德国动物健康研究院攻读博士学位，研究方向为流感病毒及新城疫病毒的血清学诊断技术。2014.5-2018.2在荷兰阿姆斯特丹大学医学院进行博士后研究，研究方向为基于CRISPR-Cas方法在清除HIV感染的SubT1细胞，并在细胞水平上实现了HIV的功能性治愈。2018-2023于广州大学生命科学学院精准基因编辑工程中心工作，研究方向为CRISPR-Cas工具的优化及新型基因编辑技术的开发。2014.10月，于赣南医科大学工作，研究方向为基于CRISPR-Cas基因编辑技术的优化及开发，以及遗传疾病或罕见遗传病的基因治疗。近年来，参与课国家自然科学基金项目2项，发表SCI学术论文10余篇。
近年发表的主要学术论文：
1.Zhao N,Zhou J, et al., Wang G, Developing a continuous directed evolution system forbase editor evolution in mammalian cells.Nature Communications, 2024. 15(1): p. 8140.
2.Zhao N, Grund C, Beer M, Wang G, Harder TC: Tetraplex Fluorescent Microbead-Based Immunoassay for the Serodiagnosis of Newcastle Disease Virus and Avian Influenza Viruses in Poultry Sera.Pathogens2022, 11(9):1059.
3.Zhao N, Grund C, Beer M, Harder TC: Engineered recombinant protein products of the avian paramyxovirus type-1 nucleocapsid and phosphoprotein genes for serological diagnosis.Virology journal2018, 15(1):8.
4.Zhao N,Wang G, Das AT, Berkhout B: Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-Resistance.Antimicrobial agents and chemotherapy2017, 61(12).
5.Zhao N,Lange E, Kubald S, Grund C, Beer M, Harder TC: Distinction of subtype-specific antibodies against European porcine influenza viruses by indirect ELISA based on recombinant hemagglutinin protein fragment-1.Virology journal2013, 10:246. (5.916/Q2)
6.Zhao N,Chen G, Fang Y, Li W, Jia H, Jing Z: Enhanced Immunity to Killed FMDV Antigen by Dual Factors Recombinant Plasmid of Porcine Interferon-gamma and CpG Motifs. Acta Veterinaria et Zootechnica Sinica 2010, 41(10):1281-1289.
7.Wang X, He S,Zhao N,Liu X, Cao Y, Zhang G, Wang G, Guo C: Development and clinical application of a novel CRISPR-Cas12a based assay for the detection of African swine fever virus.BMC Microbiol2020, 20(1):282.
8.Wang G,Zhao N,Berkhout B, Das AT: CRISPR-Cas based antiviral strategies against HIV-1.Virus research2018, 244:321-332.
9.Wang G,Zhao N,Berkhout B, Das AT: CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape.Molecular therapy: the journal of the American Society of Gene Therapy 2016, 24(3):522-526.
10.Wang G,Zhao N,Berkhout B, Das AT: A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes All Infectious Provirus in Infected T Cell Cultures.Cell reports2016, 17(11):2819-2826.
11.Henritzi D,Zhao N,Starick E, Simon G, Krog JS, Larsen LE, Reid SM, Brown IH, Chiapponi C, Foni E et al: Rapid detection and subtyping of European swine influenza viruses in porcine clinical samples by haemagglutinin- and neuraminidase-specific tetraand triplex real-time RT-PCRs.Influenza and other respiratory viruses2016, 10(6):504-517.
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